The Center is led
by Keith H. Nuechterlein, Ph.D., Professor of Psychology at the University
of California, Los Angeles, and Director of the Aftercare Program,
a research clinic for schizophrenic patients, UCLA Semel Institute
of Neuroscience and Human Behavior. Dr. Nuechterlein specializes
in neurocognitive processes in schizophrenia, especially as they
relate to both the developmental course of the disorder and to functional
outcome. Dr. Nuechterlein’s ongoing longitudinal study of the
early course of schizophrenia, “Developmental Processes in
Schizophrenic Disorders”, has closely examined the influence
of specific neurocognitive vulnerability indicators on the early
course of first-episode patients, with an emphasis on occupational
and educational outcome. He holds a joint appointment in the Department
of Psychiatry and Biobehavioral Sciences and the Department of Psychology
(Clinical and Behavioral Neuroscience areas) at UCLA.
Dr. Bearden is Associate Professor in Residence of Psychiatry and Biobehavioral
Sciences and Psychology and the Assessment Director of the CAPPS research program.
She earned her doctoral degree in Clinical Psychology from the University of
Pennsylvania in 1999. After completing a clinical internship at UC San Diego/VA
Medical Center, she completed postdoctoral training in Pedatric Cognitive Neuroscience
at the Penn/Children’s Hospital of Philadelphia, before joining the UCLA
faculty in 2003, where she was recently promoted to Associate Professor. Her
research aims to understand genetic influences on brain structure in the development
of psychosis, using converging methods to study cognition and neuroanatomy in
clinical high-risk samples (adolescents at ultra high-risk for psychosis), and
in possible ‘genetic subtypes’ of the disease with very high penetrance
(i.e., 22q11.2 microdeletion syndrome). She has received 2 NARSAD Young Investigator
Awards for her research using quantitative measures of thought disorder and functional
magnetic resonance imaging (fMRI) tasks of linguistic processing to predict outcome
in adolescents at ultra-high risk for psychosis, and those with recent onset
of psychosis. In addition, she is currently conducting an NIMH-funded project
examining neural endophenotypes of bipolar disorder in a genetically isolated
population in Latin America. For further information, please visit http://www.npi.ucla.edu/neurogenetics/members.php
R. Belin, Ph.D.
Thomas R. Belin, Ph.D., is a Professor in the UCLA Department of Biostatistics
who since 1995 has had a joint appointment in the UCLA Department of Psychiatry
and Biobehavioral Sciences. Dr. Belin came to UCLA as a post- doctoral fellow
after receiving his Ph.D. in Statistics from Harvard in 1991, where he was a
student of Donald Rubin, and he has been on the UCLA faculty since 1993. Dr.
Belin's research interests focus on incomplete-data problems and causal inference,
and he has expertise in methodologies such as multiple imputation, propensity-score
adjustment, hierarchical models, and mixture models. He was elected to be a Fellow
of the American Statistical Association in 2004, and in 2005 he received the
Gertrude M. Cox Award from the Washington (DC) Statistical Society recognizing "a
making significant contributions to statistical practice."
He has also received awards for his work in mental-health research, including
the Schlosser-Lewis Award of the American Academy of Child and Adolescent Psychiatry
(for the best paper on ADHD in 1998 in the Journal of the American Academy of
Child and Adolescent Psychiatry, with R. Bussing, et al.) and the Excellence
in Mental Health Policy and Economics Research Award - 2005/2006 (from the International
Center of Mental Health Policy and Economics for his 2005 paper with M. Edlund
and L. Tang in the Journal of Mental Health Policy and Economics). Dr. Belin
is currently an Associate Editor of the Journal of the American Statistical Association.
John Brekke, Ph.D.
John Brekke, Ph.D. is a Frances G. Larson Professor of Social
Work Research at the USC School of Social Work and Director of
the Hamovitch Center for Science in the Human Services. Dr. Brekke
is among the leaders in developing measures and measurement models
for functional outcome in major psychiatric disorders. Since
1989, he has been the principal investigator on four longitudinal
funded by the National Institute of Mental Health and one funded
by the Substance Abuse and Mental Health Services Administration.
Dr. Brekke is currently principal investigator of two studies
funded by the National Institute of Mental Health: "Biosocial Factors
in Rehabilitation for Schizophrenia" and "Predicting
Psychosocial Rehabilitation Service Outcomes." His current
research examines biosocial factors relevant to improving functional
outcomes for individuals diagnosed with schizophrenia who are
living in the community and also focuses on developing methods
and disseminating evidence-based practice methods into community
service settings for severely and persistently mentally ill individuals.
Tyrone D. Cannon, Ph.D.
Tyrone D. Cannon is the Staglin
Family Professor of Psychology, Psychiatry & Biobehavioral Sciences,
the Carol Spivak Scholar in Neuroscience, and the Director of the
Staglin Music Festival Center
for Cognitive Neuroscience at UCLA. Dr. Cannon earned his bachelor’s
degree at Dartmouth College (1985) and his doctoral degree at the
University of Southern California (1990). He spent a year in clinical
training at the UCLA Neuropsychiatric Institute (1990-1991), before
taking his first academic appointment in the Department of Psychology
at the University of Pennsylvania, where he was promoted to associate
professor with tenure in 1997. He joined the faculty at UCLA in 1999.
Dr. Cannon’s research aims to discover the causes of schizophrenia
and bipolar disorder and to develop effective treatment and prevention
strategies based on an understanding of the genetic and neural mechanisms
that give rise to these disorders. His studies have focused on elucidating
the genetic and non-genetic factors that influence susceptibility
to schizophrenia and bipolar disorder and delineating their effects
on brain structure and functioning across development, with a particular
emphasis on gestational (pre- and perinatal) and adolescent periods
of brain development A hallmark of his work is the integration of
molecular biological and neuroimaging approaches in unique populations
such as twins discordant for schizophrenia and bipolar disorder and
selected members of large prospectively evaluated birth cohorts who
have developed one of these conditions in adulthood. Recent work
has incorporated transgenic animal models and has extended this translational
human-animal genetics and neuroscience strategy to Neurofibromatosis
1, an inherited condition affecting brain structure and function.
With support from the Music Festival for Mental Health and the National
Institute of Mental Health, Dr. Cannon has established a clinical
research center for early detection and prevention of major mental
illness in at risk youth based in the UCLA Neuropsychiatric Institute.
In that project he and his colleagues are ascertaining individuals
who are at risk for imminent onset of psychosis and following them
in longitudinal neuroimaging studies aimed at identifying the neural
changes that occur proximally to onset of psychosis. For further
information, please call (310) 206-8765, email email@example.com,
or visit http://www.schizophrenia.ucla.edu/prevention, cannonlab.psych.ucla.eduhttp://www.cannonlab.psych.ucla.edu,
Page Fiske, Ph.D.
Alan Page Fiske, Ph.D., is Professor in the Department of Anthropology, UCLA.
He is a psychological anthropologist who worked in Africa for eight years. His
primary research goal is to understand how human social relationships are shaped
by the coordination of psychology, culture, ontogeny, evolution, neuroanatomy
and neurochemistry. He is best known for his relational
models theory and research
showing that there are only four fundamental, universal forms of intrinsically
motivated social coordination. He also leads a research team studying social
motives and moral emotions in frontotemporal
dementia, and has studied OCD and
personality disorders. He is one of the founders and past directors of the UCLA
Center for Behavior, Evolution, and Culture; and of the FPR-UCLA Center for Culture,
Brain, and Development. For further information, please visit http://www.sscnet.ucla.edu/anthro/faculty/fiske/.
Michael Foster Green, Ph.D.
Michael Foster Green, Ph.D. is a Professor-in-Residence in the Department
of Psychiatry and Biobehavioral Sciences at the Geffen School of
Medicine at UCLA, and is Director of the Treatment Unit of the Department
of Veteran Affairs VISN 22 Mental Illness Research, Education, and
Clinical Center (MIRECC). Dr. Green obtained his B.A. in psychobiology
at Oberlin College, his doctorate in neuropsychology at Cornell University,
and his postdoctoral training in neuropsychology at UCLA. He is on
the editorial boards of Cognitive Neuropsychiatry, Schizophrenia
Research, and Schizophrenia Bulletin and has authored over 130 journal
articles. He has received numerous grants from NIMH, the Veterans
Administration, and private foundations. His research activities
have been devoted to understanding the nature and implications of
cognitive dysfunction in schizophrenia, including neurocognitive
indicators of genetic vulnerability to schizophrenia and neural mechanisms
of cognitive dysfunction. His laboratory has explored the relationship
between cognitive deficits in schizophrenia and activities of daily
living, and the neurocognitive effects of antipsychotic and adjunctive
medications. He has written two books: Schizophrenia from a Neurocognitive
Perspective: Probing the Impenetrable Darkness, published in 1998,
and Schizophrenia Revealed: From Neurons to Social Interactions,
published in 2001. Dr. Green is a past president of the Society for
Research in Psychopathology. For further information, please visit
Gerhard Hellemann, Ph.D., SIStat Senior Statistician, received his doctorate
in psychology from UCLA where he studied psychometrics under Dr. Peter Bentler.
Dr. Hellemann has both theoretical and practical experience with mixed models,
hierarchical data, structural equation modeling, factor analysis, and path
modeling techniques, all of which are essential for this center’s research.
He has worked closely with many of the project scientists both during his graduate
studies and more recently as a SIStat consultant. He has played a key role
in the center’s initial cross-project analyses.
P. Horan, Ph.D.
William P. Horan, Ph.D., is an Associate Research Psychologist in the Department
of Psychiatry & Biobehavioral Sciences at UCLA. Dr. Horan completed his Ph.D.
in clinical psychology at the University of New Mexico, a clinical internship
at the Western Psychiatric Institute & Clinic in Pittsburgh, PA, and a post-doctoral
fellowship at UCLA. He investigates emotional, social cognitive, and neurocognitive
processes in schizophrenia, and how disturbances in these areas impact functional
outcome. Specific research interests include negative symptoms, translation of
concepts and methods from basic affective and social cognitive neuroscience to
studies of schizophrenia, and psychosocial treatments for people with severe
mental illnesses. For further information, please visit http://greenlab.npih.ucla.edu/Overview.htm.
Sook Hwang, M.S.
Sun Sook Hwang, M.S., Manager of SIStat, has supervisory responsibility for
the routine data management and programming necessary to support the individual
projects, and supervises the overall day to day activities of the unit. She
has received her Master’s degree in Biostatistics in 1985 at UCLA and
has been working at SIStat since then. She has more than 20 years of experience
on statistical consulting and data management. She handles varied tasks that
require knowledge of computer languages and creates data files for investigators,
supervises file updating, cleaning and maintenance. She has published about
20 papers in Mental Health research.
S. Kee, Ph.D.
Kimmy S. Kee, Ph.D., is an Associate Professor of Psychology at California State
University, Channel Islands, and is also an Assistant Research Psychologist in
the Department of Psychiatry and Biobehavioral Sciences at UCLA. Dr. Kee earned
her Ph.D. in Clinical Psychology from Medical College of Pennsylvania and Hahnemann
University in Philadelphia. Subsequently, she pursued her post-doctoral training
in schizophrenia research at UCLA. Her research interests within schizophrenia
include neurocognitive and social cognitive processes and psychosocial functioning.
She has systematically explored the nature, determinants, and treatments for
deficits in emotion processing through a series of projects funded through grants
from the NIMH, Veterans Administration, Stanley Foundation, and Janssen Research
Foundation. For further information, please visit http://greenlab.npih.ucla.edu/Overview.htm.
Barbara Knowlton, PhD, is a Professor in the Behavioral Neuroscience
area of the Department of Psychology. She is the basic cognitive
neuroscience collaborator of Dr. Cannon for the project on “Encoding
and Retrieval in Long-Term Memory”. The focus of Dr. Knowlton’s
work is the study of the neural bases of memory. Her lab uses a
number of different approaches in humans and animal models in order
to describe functional differences between memory systems and the
brain systems that support them. One area of particular interest
is on the dissociation between episodic and non-episodic memory
and the differential involvement of hippocampus in the former.
Additional work evaluates the neural basis of executive function
by testing neuropsychological patients.
J. Lang, Ph.D.
Peter J. Lang, Ph.D. is a Graduate Research Professor in the Department of Clinical
and Health Psychology at the University of Florida, Gainesville and the Director
of the NIMH Center for the Study of Emotion and Attention. Dr. Lang is an internationally
recognized authority on the study of emotion. He is the recipient of many honors
and awards, most notably the Award for Distinguished Contributions to Psychophysiology
from the Society for Psychophysiological Research and the Distinguished Scientific
Contribution Award from the American Psychological Association. For further information,
please visit http://csea.phhp.ufl.edu/.
Gang Li, Ph.D., is a Professor in the Department of Biostatistics in the UCLA
School of Public Health. Dr. Li, who was recently elected a fellow of the Institute
of Mathematical Statistics, is an internationally recognized expert in longitudinal
modeling and survival analysis. He has worked on developing statistical methods
for the analysis of clinical trials and epidemiologic studies in which the
time to an event is a primary outcome, as well as nonparametric regression,
model selection, nonparametric and semiparametric likelihood ratio based inference,
two-sample problems, and bootstrapping for censored, truncated, and biased
data. His collaborative work in mental health research involves developing
and applying statistical methods to understand schizophrenia, developmental
neuropyschiatric disorders, and neurophysiological phenomena such as prepulse
inhibition of startle. He has also been involved in survey research on mate
availability, marital attitudes and mental health. Dr. Li will consult directly
with investigators and through Dr. Sugar concerning appropriate structural
and longitudinal models for center data.
Jim Mintz, Ph.D., is a Professor with joint appointments in
the Department of Psychiatry and Biobehavioral Sciences, UCLA
School of Medicine, and the
Department of Biostatistics, UCLA School of Public Health. Dr. Mintz received
his graduate training as a student of Jacob Cohen at NYU during the 1960s.
He is past President of the Society for Psychotherapy Research. He served as
a Member of the Clinical Research Center & Program Projects and the Mental
Health Services Research Review Committees at NIMH. Dr. Mintz has published
more than 300 scientific papers in peer-reviewer journals on topics covering
most areas of psychiatric science.
Harold Pashler, Ph.D., a Professor of the University of California,
San Diego Department of Psychology. Dr. Pashler received the 1999
Troland Prize from the National Academy of Sciences "for his
many experimental breakthroughs in the study of spatial attention
and executive control, and for his insightful analysis of human
cognitive architecture". For further information, please visit http://laplab.ucsd.edu/.
Mark Sergi, Ph.D. is an associate professor in the Department
of Psychology at California State University Northridge. Dr.
Sergi earned his doctorate in clinical psychology at the State
University of New York at Binghamton in 1998 and completed
a two-year postdoctoral fellowship at UCLA in 2000. Dr. Sergi’s
research concerns relations between neurocognition, social
cognition, and functional status in persons with schizophrenia
and related disorders. He has published many articles in journals
such as the American Journal of Psychiatry, Schizophrenia Bulletin,
and Schizophrenia Research. Dr. Sergi is a licensed clinical
psychologist with a part-time clinical practice in Tarzana,
Kuo-Chung Shih, M.A., Programmer Analyst III, is a leading programmer in SIStat
and is an experienced web developer and designer. He gained his B.A. degree in
Fine Arts and has 8 years of working experience in graphic design and 6 years
in web design and application development. He particularly focuses on web-based
Electronic Data Capture (EDC) solution for research studies. The primary aims
of development are to develop real-time management reporting and analysis applications
with an intuitive, workflow-based graphical user interface and to integrate the
works of project management, data collection and analysis in one central station.
He is responsible for developing, maintaining and design of all web based programs
for patient scheduling, center patient registry, and reliability calculation.
He also troubleshoots hardware and software problems that may arise.
Kenneth Subotnik, Ph.D.
Kenneth Subotnik, Ph.D. is a Research Psychologist
and Adjunct Professor of the Department of Psychiatry & Biobehavioral
Sciences. He is the Associate Director of the Aftercare Research
co-Director of the Chronic Schizophrenia Recruitment and Assessment
Core. He received his Ph.D. from the UCLA Department of Psychology
in 1990. His areas of special research interest include, the examination
of psychometric vulnerability indicators in schizophrenia patients
and their family members, with a focus on measures such as the Minnesota
Multiphasic Personality Inventory (MMPI); 2) the examination of formal
thought disorder and its relationship to neurocognitive and neuroanatomical
abnormalities; 3) the early course of “positive” and “negative” schizophrenia
symptoms and their clinical correlates; and 4) the examination of
psychological factors affecting medication adherence, such as insight
and attitudes toward antipsychotic medication.
Catherine Sugar, Ph.D. is an Assistant Professor in the Department of Biostatistics
and the Director of the Semel Institute Statistics Core (SIStat) in
the Department of Psychiatry at the University of California, Los Angeles.
She received her Ph.D. in statsitics from Stanford University in 1998. Dr.
Sugar's methodological expertise is in clustering, classification, and functional
data analysis with an emphasis on finding patterns in high-dimensional or longitudinal
data. She has also been involved in numerous applied projects in the mental
health arena, particularly in schizophrenia and depression. This work has focused
on identifying patterns of symptoms or functioning in patient populations and
exploring how those patterns evolve over time in response to treatments or
E. Taylor, Ph.D.
Shelley E. Taylor, Ph.D. is a Distinguished Professor in the Department of
Psychology at the University of California, Los Angeles. She is a preeminent
social scientist who studies social support, self-regulation, stress, coping
and health psychology. Dr. Taylor’s numerous honors and awards include
the Distinguished Scientific Contribution Award from the American Psychological
Association, the Outstanding Scientific Contribution Award in Health Psychology
and election to the Institute of Medicine, National Academies of Science.
Additional information about Dr. Taylor and her research lab is available
G.M. van Erp, Ph.D.
Theo G.M. van Erp, Ph.D., has an academic appointment as an Assistant Researcher
in the Clinical Neuroscience Laboratory in the Department of Psychology at UCLA.
He earned his bachelor’s and Master’s degrees in neuropsychology
at the University of Nijmegen (1996) and his doctoral degree at the University
of Utrecht (2007) in the Netherlands. He spent a year (1995-1996) in clinical
and research training in the Brain Behavior Center at the University of Pennsylvania,
before taking a position with Dr. Tyrone D. Cannon in the Clinical Neuroscience
(CNS) Laboratory at the Department of Psychology at the University of Pennsylvania,
where he became the lab manager. He moved with the CNS Laboratory to UCLA in
1999. Dr. Van Erp’s research interests focus on understanding the nature,
sources (genetic / environmental), and pathogenesis (development) of the neural
mechanisms underlying schizophrenia and bipolar disorder, through the use of
behavioral, brain morphological (MRI), biochemical (MRS), and functional (fMRI)
measures. His Ph.D. thesis focused on understanding the sources of hippocampal
morphological abnormalities and the nature and the sources of episodic memory
abnormalities in schizophrenia. Dr. Van Erp has numerous published works on neurobiological
endophenotypes for schizophrenia. For further information, please call (310)
206-4902, email firstname.lastname@example.org, or see http://vanerp.bol.ucla.edu,
Joseph Ventura, Ph.D., is a Senior Research Psychologist and member
of the Faculty in the UCLA
Department of Psychiatry & Biobehavioral Sciences. Dr. Ventura
and his colleagues have developed and published a set of internationally
recognized diagnostic and symptom assessment training and quality
assurance procedures. He is responsible for all training and quality
assurance functions, development, standardization, and refinement
of the Center's diagnostic and psychiatric symptom assessment procedures.
Cindy M. Yee-Bradbury, Ph.D.
Cindy M. Yee-Bradbury, Ph.D. is an Associate Professor in the Department
of Psychology at the University of California, Los Angeles (UCLA)
and in the Department of Psychiatry and Biobehavioral Sciences at
the UCLA Geffen School of Medicine. Dr. Yee-Bradbury received her
doctorate in clinical psychology from the University of Illinois
at Urbana-Champaign, and completed her clinical internship training
at the UCLA Neuropsychiatric Institute. Her current research focuses
on neurocognitive vulnerability to schizophrenia and on the relationship
between stress and emotion to vulnerability to schizophrenia, emphasizing
the interrelationships between physiological, psychological and social
aspects of behavior. Dr. Yee-Bradbury directs the Laboratory on Clinical
Affective Psychophysiology which relies upon dense array recordings
of EEG activity along with measures of autonomic nervous system activity
and neuroendocrine response to complement interview and behavioral
measures of clinical symptoms, life stress and coping. For further
information, please visit http://lcap.psych.ucla.edu/.
2006 Center for Neurocognition and Emotion in Schizophrenia all rights